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  JBC: Instructions for Authors

*Table of Content*

How to submit <#_How_to_Submit>

      Submission Fee <#_Fee>
      Initial Manuscript Submission <#_Initial_Manuscript_Submission>
      Revised Manuscript Submission <#_Revised_Manuscript_Submission>
      Accelerated Publication Submission <#AcceleratedPublication>
      Final Submission of an Accepted Manuscript
      <#_Final_Submission_of_an_Accepted_Man>

Organization of the Manuscript <#_Organization_of_the_Manuscript>

      Text <#_TEXT>
      References <#_References>
      Tables and Figures <#_Tables_and_Figures>
      RGB Workflow <#_New_RGB_Workflow>
      Supplemental Data <#supplemental_data> 

Publication Charges <#PubCharges>

    Page Charges <#PubCharges>
    Color Figures <#PubCharges>
    Halftones <#PubCharges>
    Reprints <#PubCharges>

Chemical and Mathematical Usage <#_Chemical_and_Mathematical_Usage>
Protein and Nucleic Acid Sequences <#_Protein_and_Nucleic_Acid_Sequences>
Genomic and Proteomic Studies <#_Crystallographic_Studies>
Crystallographic Studies <#_Crystallographic_Studies>
Database Accession Hyperlinks For JBC On-line
<#_Database_Accession_Hyperlinks_For_J>


    General Requirements

All submitted manuscripts should contain original research not
previously published and not under consideration^ for publication
elsewhere. Papers may come from any country but must be written in
English. All submissions must be accompanied by abstracts of the
authors' manuscripts on related subjects that are in press or currently
under editorial review. Electronic reprints of related published papers
by the authors or manuscripts in press may also be helpful to the
reviewers.

Manuscripts may be submitted for consideration as Regular Papers or
Accelerated Publications.  The JOURNAL also publishes Minireviews, all
of which are by invitation only. Authors are urged to keep the length of
Regular Papers to six printed pages or less. Accelerated Publications
can be no longer than five printed pages, including all spaces,
references, figures and tables.   A five page paper is usually less than
30,000 characters plus two figures or tables (if each figure or table is
less than 1/4 page).


  How to Submit


          Submission Fee:  Beginning September 12, 2006 there will be a
          one-time mandatory submission fee of $60 for each article
          submitted.


        *Authors are required to submit manuscripts electronically using
        the Online Submission and Review System (OSRS) available at
        http://www.jbc.org/submit.   All manuscript must be submitted in
        PDF ** format. *


    Submission Fee

There will be a one-time mandatory submission fee of *$60* for each
article submitted.  Manuscripts will not be processed until the fee is
received.

Back to the top <#_top>


    Initial Manuscript Submission

1. Prepare the text in Microsoft Word 6.0 (Word 2001 for Mac) or a later
version.

In preparing the Word text document create a format that produces a
manuscript that has an appearance similar to that of a published paper.
If your paper is accepted, a PDF version of the manuscript is published
as /JBC Papers in Press/ and the effort of formatting will yield a more
attractive, readable publication. The document should have the
approximate appearance and layout shown (details below):

<http://www.jbc.org/misc/ms_sample.pdf>

See a complete example of the manuscript?s format
<http://www.jbc.org/misc/ms_sample.pdf>

All of the text should be single spaced with one-inch margins on the
left and right sides.  Once the text of the manuscript is completed in
Word, convert the Summary through Discussion sections from a single
column format to double column format.  Select these sections of the
text, click on ?Format? heading, then ?Columns? from the drop-down menu.
Select two columns and equal column width and then change spacing to
0.25 inches.  Title and running title sections as well as references,
footnotes, figure legends and tables should remain in single column format.

Use Times New Roman font and select size and bolding to mimic the
appearance shown above for the title section; use 11 point for the
remaining text.

Do not imbed graphics in the Word document but add them at the end of
the PDF as described below.

2. Prepare figures at publication quality resolution, using only
applications capable of generating high resolution TIFF or EPS files.
Number each figure. For important requirements information on the
preparation of figures, go to http://art.cadmus.com/da/jbc/index.jsp.
Rapid Inspector is now available for use by authors.  The Rapid
Inspector software allows authors to check their figure files against
JBC standards for format, resolution, color space and other figure
requirements.  Click here to download Rapid Inspector
<http://rapidinspector.cadmus.com/zbc> to your computer.

3. Using Adobe Acrobat (see http://adobe.com/products/main.html for
information), save your manuscript text and figures in a single file in
PDF format with the figures at the end. The file name should be one word
with no spaces and a .pdf extension at the end ( e.g. manuscript.pdf ).
Authors are responsible for assuring the accuracy and quality of the
PDF.  Please consult your Adobe Acrobat manual for instructions
regarding PDF file creation.

 4. Print the PDF file and carefully review text and figures. It is the
author?s responsibility to assure that the manuscript is suitable for
review, particularly figures. Manuscripts that do not have figures of
sufficient quality for scientific review will be returned to authors.
Check the PDF file size. Most files should be around 1 MB, but not
larger than 5 MB. If the file is larger than 5 MB, you may adjust the
default settings of Adobe Acrobat to create a smaller size file. We will
not process your submission if your PDF is larger than 5 MB. If you need
help, please contact the JBC office at jbc@asbmb.org <mailto:jbc@asbmb.org>

5. Submit your manuscript at http://www.jbc.org/submit. You will need:

    * Contact information for the Submitting Author
    * Information about the authors and the manuscript
    * A cover letter with information for the Editor and Associate Editors
    * Single PDF file of your manuscript under 5 MB in size. *This file
      should contain text and figures.*

Back to the top <#_top>


    Revised Manuscript Submission

Revised manuscripts are prepared exactly as described above for initial
submission and submitted via the JBC submission system at
http://www.jbc.org/submit. Responses to raised concerns should be
transmitted in the cover letter, not in the PDF file containing the
manuscript.


    Accelerated Publication Submission

Accelerated Publications are intended to present new information of
exceptional novelty, importance and interest to the broad readership of
the JOURNAL. Accelerated Publications must be five printed pages or
less, including all figures, references and tables. A standard 5 page
paper contains 30,000 characters, including spaces, plus 2 tables or
figures. They are not intended simply to be short versions of Regular
Papers. Because the criteria for acceptance of Accelerated Publications
are considerably more stringent and the review process is expedited, an
Associate Editor may judge a manuscript unsuitable without obtaining a
full review.


    Final Submission of an Accepted Manuscript

          If your manuscript is accepted for publication by JBC, the
final PDF version will be published as a JBC Papers in Press within 24
hours of acceptance.

            You are then required to send the final version as source
files including a separate Word file for text and graphic TIFF and EPS
files for the figures directly to Cadmus Professional Communications via
their FTP site.  Specific instructions will follow acceptance of the
manuscript. These files must be exactly the same files from which the
final PDF was prepared; otherwise they will be rejected, delaying
publication.

Back to the top <#_top>


  Organization of the Manuscript

1. Formatted for 8.5 x 11 inch paper
2. Single spacing throughout
3. Two column page format including Summary through Discussion
sections.  Title section as well as references, footnotes, figure
legends and tables at the end of the manuscript are in single column
format. Click here to see an example
<http://www.jbc.org/misc/ms_sample.pdf>.
4. One-inch left and right margins and 0.25 inch spacing between columns.
5. Text typed in Times New Roman, 11 point
6. Manuscript is to be arranged in the following order:

      (a) title, author(s), and complete name(s) of institution(s) and
      running title
      (b) summary
      (c) introduction
      (d) experimental procedures
      (e) results
      (f) discussion
      (g) references
      (h) footnotes
      (i) figure legends
      (j) tables
      (k) figures
      (l) supplemental data ( if applicable )

7. Number all pages including figures. Please note:  Any paper submitted
without page numbers will be deleted and you will be asked to resubmit
with pages numbers using the online submission system.


    TEXT

Title Section

·        Title - as short and informative as possible, should not
contain non-standard   acronyms or abbreviations and should not exceed
two printed lines

·        Authors - contains names of all authors and their complete
mailing addresses and    identifies who will receive all correspondence
regarding the manuscript,    including proofs:

      a) name
      b) telephone and fax numbers
      c) email address 

·        Running Title - will be at the top of each printed page and
cannot exceed 60 characters and spaces

·        Summary

    * should succinctly and clearly describe the major findings reported
      in the manuscript
    * must not exceed 250 words nor contain abbreviations or specialized
      terms
    * should be understandable in itself, since it is frequently used as
      an abstract

·        Introduction

    * presents the purpose of the studies reported and their
      relationship to earlier work in the field
    * should not be an extensive review of the literature nor, in
      general, exceed one typed page

·        Experimental Procedures

    * brief but sufficiently complete to permit a qualified reader to
      repeat the experiments reported
    * only truly new procedures should be described in detail
    * cite previously published procedures in References
    * modifications of previously published procedures not given in
      detail except when necessary to repeat the work

·        Results

    * presented in figures and tables
    * some results not requiring documentation given solely in the text
    * extensive discussion not in Results section

·        Discussion

    * concise (usually less than two typed pages)
    * focused on the interpretation of the results rather than a
      repetition of the Results section

Back to the top <#_top>


    References

    * cited in text by number rather than author and date
    * numbered consecutively in the order of appearance in the manuscript
    * References for journals and books should be in the following styles:

            1. MacDonald, G. M., Steenhuis, J. J., and Barry, B. A.
(1995) /J. Biol. Chem. /*270*,    8420-8428

            2. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989)
/Molecular Cloning: A Laboratory Manual,/ 2nd Ed., Cold Spring
HarborLaboratory, Cold Spring Harbor, NY

Journal names are abbreviated according to Chemical Abstracts
(http://www.cas.org/). Authors are fully responsible for the accuracy of
the references.

Miscellaneous

·        /Footnotes/ are used to cite manuscripts in preparation,
unpublished observations, and personal communications. Authors are
responsible for obtaining written approval for all personal
communications and sending a copy of the manuscript to those cited. The
Editor may request proof of such approval.

·        All /abbreviations/ used in the text must be defined in a
single footnote inserted in the text immediately after the first
abbreviation is cited. The abbreviations of some important biochemical
compounds, /e.g. /ATP, NADH, DNA, and amino acids in proteins, need not
be defined. Phrases such as "central nervous system" or "red blood
cells" should not be abbreviated. Names of enzymes are usually not
abbreviated except in terms of the substrates for which there are
accepted abbreviations, /e.g. /ATPase and RNase.

·        The /trivial and systematic names of enzymes/ should be those
recommended by the Nomenclature Committee of the International Union of
Biochemistry and Molecular Biology (IUBMB) in "Enzyme Nomenclature,
Recommendations, 1992
<http://www.chem.qmw.ac.uk/iupac/bibliog/white.html>/" (1992, Academic
Press)./

·        Notes added in proof to a manuscript only with the consent of
the Associate Editor

·        Errors in a published paper will be corrected in the JOURNAL in
"Additions and Corrections"  

Back to the top <#_top>


    Tables and Figures

The number of tables and figures used to present data essential to
illustrate or prove a point should be kept to a minimum. Very complex or
large tables should be submitted as a figure or as a supplement to JBC
On-line. For example,^ amino acid or nucleic acid sequences with
alignments*. *It is also possible to submit complex data that is
difficult to print as a supplement to JBC On-line (see below).

*/Tables/* should have titles and sufficient experimental detail in a
legend immediately following the title to be understandable without
reference to the text. Each column in a table must have a heading, and
abbreviations, when necessary, should be defined in the legend.

*/Figures/* should have titles and explanatory legends containing
sufficient detail to make the figure easily understood. All legends
should be printed consecutively in a separate section of the manuscript.
 Authors are responsible for providing digital art that has been
properly sized and cropped.  Appropriately sized numbers, letters, and
symbols should be used so they are no smaller than 2 mm in size after
reduction to a single column width (20 picas, 8.7 cm, 3.25 inches), a
1.5-column width (29 picas, 12.0 cm, 4.75 inches), or a full 2-column
width (42 picas, 17.8 cm, 7 inches). Superscript and subscript
characters are not excluded from this rule. Numbers, letters, and
symbols used in multi-paneled figures must be consistent. The abscissa
and ordinate should be clearly labeled with appropriately sized type,
and units of measurement must be given. *Failure to comply with these
specifications will require new figures and delay publication*. Scales
for plotting the data should be marked by short index lines, but every
index line need not be numbered. Use standard symbols found in MS Word
with symbols and curves identified in the legend and not on the figure.*
*Indicate the figure number on the front of each figure.

All figures should be created with applications that are capable of
preparing high resolution TIFF or EPS files acceptable for publication.
Although you will initially submit figures with the text in a single PDF
file, we will require submission of figures as separate TIFF or EPS
files at publication quality resolution for print and online publication
if your paper is accepted. For important information on the preparation
of figures in TIFF or EPS, go to
http://art.cadmus.com/da/jbc/index.jsp.  The list of acceptable graphic
Mac OS and Microsoft Windows applications may be found at
http://art.cadmus.com/da/jbc/applications.jsp. These applications can be
used to successfully create high quality TIFF and EPS files and you will
find instructions on how to save them properly at this URL. Because more
applications are added as testing continues, please review this list
periodically.  It is the author's responsibility to verify the quality
of the graphics in the PDF that has been prepared and that compression
of the files for submission does not distort the images.

While image manipulation is often desirable for clarity and/or brevity
of presentation, manipulation for deceptive purposes either to unfairly
enhance or eliminate or otherwise obscure data is misconduct and will be
resolved according to Journal policy.

For graphic material, we have adopted a policy taken from The Journal of
Cell Biology <http://www.jcb.org/misc/ifora.shtml#image_acquisition>.

?/No specific feature within an image may be enhanced, obscured, moved,
removed, or introduced. The groupings of images from different parts of
the same gel, or from different gels, fields or exposures must be made
explicit by the arrangement of the figure (e.g. using dividing lines)
and in the text of the figure legend. Adjustments of brightness,
contrast, or color balance are acceptable if and as long as they do not
obscure or eliminate any information present in the original. Nonlinear
adjustments (e.g. changes to gamma settings) must be disclosed in the
figure legend./?

Please be aware of several key issues when preparing graphics for
publication:

   1.

      *The JBC is now in an RGB (Red, Green, Blue) workflow for color
      figures.* Prior to June 1, 2005, authors were required to submit
      figures in CMYK (Cyan, Magenta, Yellow, blacK) color mode, as this
      is the native color mode for the printing process and thus
      optimizes color for press. *As of June 1 2005, all color figures
      should be submitted in RGB format.* Images supplied by authors in
      RGB color will retain the brilliant reds, greens, and blues for
      online publication, but may experience a color shift in printed
      form. To learn more, please see
      http://art.cadmus.com/da/jbc/index.jsp
      <http://art.cadmus.com/da/jbc/guidelines_rgb.jsp>

   2.

      Images supplied in EPS format should have all fonts converted to
      outlines/paths. If fonts are not converted to paths or outlines,
      there is a possibility of character substitutions or that your
      graphic may have to be converted to a bitmap, which can affect
      online image quality. The following screenshot demonstrates how to
      convert fonts to outlines/paths in Adobe Illustrator:

   3. *Excessive file compression for submission can distort images so
      that PDFs should be carefully checked. *

* *

#

*Images containing both greyscale and bitmap areas must be supplied at a
minimum resolution of 600 dpi. If possible, it is best to prepare such
images as vector files for the line art areas, with embedded TIFF images
for the greyscale portions.*

#

*We cannot accept figure files in certain applications such as Microsoft
Office (PowerPoint, Word, Excel, Access), Corel Perfect Office
(WordPerfect, Quattro Pro, Presentations), Lotus SmartSuite (Freelance
Graphics, 1-2-3, Approach, and WordPro). They are not intended for high
resolution imaging necessary for publication. For example, problems with
PowerPoint that impact both the visual quality and accuracy of print
reproduction include:*

    *

      Poor Color Reproduction - PowerPoint files are intended for screen
      display (RGB color model) and must be color separated for creation
      of printing plates involving transformation to CMYK color
      (commercial printing). Colors that are represented in a PowerPoint
      presentation may not be possible to reproduce on printing.

    * *Lack of resolution control - Because PowerPoint is intended for
      screen displays rather than print production; it does not offer
      full control over resolution.  Lettering and other figure parts
      may appear jagged.*

    * *Poor Font Management - If a computer does not have a font in a
      PowerPoint presentation created on another computer, it will
      substitute the font (usually with nonsense) without warning.*

To learn how to convert PowerPoint images to an acceptable format for
publication, please see:
https://rapidsubmission.cadmus.com/jbc/JBC%20PowerPoint%20Update.pdf

Below are examples of a good quality figure and a poor quality figure. 
The good quality figure has all the wording on the figure in proportion
whereas the poor quality figure has a wide variety of lettering sizes.
	
*Bad Quality Figure * 	*Good Quality Figure *

After a manuscript is judged acceptable for publication by JBC the
figure TIFF and EPS files as well as the Word text file will be
submitted online at a FTP site maintained by Cadmus Professional
Communications.  Specific instructions will follow acceptance of the
manuscript.

There will be a charge of $25 per figure for publication of halftone
figures. We encourage authors to use color figures when they will
enhance the presentation of the data. The cost is $300 for each
illustration containing color. (Note: When using the electronic
submission system, any figure submitted in color will be reviewed and
processed with the understanding that the figure will be published in
color.)

If you require further information, please send an email query to
jbc@asbmb.org <mailto:jbc@asbmb.org>

Back to the top <#_top>


    Supplemental Data

The JBC On-line provides the opportunity for authors to include data
impossible or impractical to include in the printed JOURNAL. We feel
that the ability to include such data in JBC On-line will substantially
enhance an author's ability to communicate important research
information and will also greatly benefit readers.

We strongly encourage authors to include data such as videos, 3-D
structures/images, sequence alignments, and data sets that are very
large such as those obtained with microarray hybridization experiments.
These data will be reviewed as a part of the normal manuscript review
process and will be judged by the same criteria. Only data that are
uniquely suited to the On-line journal and which substantially
contribute to the manuscript will be accepted.  Data files can be
prepared in Plain Text, MS Word, HTML Page, MS Excel, TIFF, JPEG or GIF.
When practical supplemental data files should be converted and submitted
as PDF files. Movies and large excel files should be submitted in their
native formats.

Videos should be submitted as QuickTime Video, MPEG movie or MS AVI
video and may be prepared on either a PC or Mac computer. All videos
should be submitted at the desired reproduction size and length. To
avoid excessive delays in downloading the files, videos should be no
more than 5 MB in size and 30 and 60 seconds in length. Authors are
encouraged to use QuickTime's "compress" option when preparing files to
help control file size. Additionally, cropping frames and image sizes
can significantly reduce file sizes. Files submitted can be looped to
play more than once, provided file size does not become excessive.
Authors will be notified if problems exist with videos as submitted and
will be asked to modify them. No editing will be done to the videos at
the editorial office. All changes are the responsibility of the author.

File name(s) should be one word with no spaces and the appropriate
extension at the end. ( e.g. movie1.mov, movie2.qt, table1.xls ).

IMPORTANT: One traditional still image of the author's choosing must be
submitted per video. This image will be published to act as a link from
the text to the full video file. It will also appear in the text of the
printed journal in place of the video. Please indicate clearly in your
text whether a figure has a video associated with it and be sure to
indicate the name of the corresponding video file. A brief figure legend
should also be provided. The figures should be prepared using the
guidelines for figures indicated earlier in these instructions. For more
information regarding the submission of videos, please contact the JBC
editorial office.

Back to the top <#_top>


    *Publication Charges *

    *Page Charges --* $75 per journal page
    *Color Figures* *--* We encourage authors to use color figures when
    they will enhance the presentation of the data. The cost is $300 for
    each illustration containing color. (Note: When using the electronic
    submission system, any figure submitted in color will be reviewed
    and processed with the understanding that the figure will be
    published in color.)
    *Halftones --* $25 per figure*
    Reprints ?* Pricing is based on quantity ordered.

    Back to the top <#_top>


  Chemical and Mathematical Usage

Table I lists the abbreviations for units of measurement and certain
physical and chemical quantities used by the JOURNAL without definition.
Also listed are the prefixes that can be added^ to names of units and
the multipliers indicated by each prefix. 


*View this table:*
[in this window] <http://www.jbc.org/misc/itoa.TI.shtml>

	

*Table I*
*Abbreviations of units of measurement and of physical and chemical
quantities *

(These abbreviations may be used without definition. They are not
followed by periods. The same form is used in the plural.) 

The JOURNAL recommends the use of the International System of Units (SI)
(Page, C. H., and Vigoureux, P., Editors, NBS Special Publication 330,
U.S. Government Printing Office; see also the IUPAC Manual of Symbols
and Terminology for Physicochemical Quantities and Units (1979) Pergamon
Press). However, it will continue to accept certain units as listed here
(/e.g./ angstrom, calorie, minute) even though they are not part of the
SI. Note that wavelength should be expressed in nanometers or in
angstrom units; millimicron is specifically unacceptable. 

Chemical equations, structural formulas, and mathematical equations
should be placed between successive lines of text. In general,^ the
rules and recommendations of the IUBMB and the International^ Union of
Pure and Applied Chemistry (IUPAC) will be used for abbreviation^ of
chemical names, nomenclature of chemical compounds, enzyme^
nomenclature, isotopic compounds, optically active isomers, and
spectroscopic data. We recommend the use of the classification,
nomenclature, and structural representation of lipids used by the LIPID
MAPS Initiative (see Fahy et al.
<http://www.jlr.org/cgi/content/abstract/46/5/839> /J. Lipid Res./ 2005
46: 839-862). You can download lipid structures directly from the LIPID
MAPS Structure Database (http://www.lipidmaps.org). This database draws
structures de novo, allowing you to insert them into your documents.
Table II <#TII> lists references to publications^ of the rules and
recommendations of the International Scientific^ Unions that may be
consulted for detailed information.  


*View this table:*
[in this window] <http://www.jbc.org/misc/itoa.TII.shtml>

	

*Table II*
*Tentative Rules and Recommendations of International Scientific Unions *

*Many of the documents in this table can be obtained on the internet at
http://www.chem.qmw.ac.uk/iupac/index.html.*

Back to the top <#_top>


  Protein and Nucleic Acid Sequences

Newly reported nucleotide or protein sequences must be deposited in
GenBank or EMBL databases, and an accession number must be obtained
BEFORE the paper is accepted by the Associate Editor. Access to the
information in the database must be available at the time of
publication. /Authors are responsible for arranging release of data at
the time of publication. The authors must also provide a statement in
the manuscript that this sequence has been scanned against the database
and all sequences with significant relatedness to the new sequence
identified (and their accession numbers included). /

Authors of accepted papers containing nucleotide sequences must submit
the sequence data, preferably in computer-readable form or by electronic
mail, and a copy of the paper to either:

*GenBank*

    GenBank Submissions
    National Center for Biotechnology Information
    8600 Rockville Pike, Building 38A
    Room 8N-805
    Bethesda, MD 20894
    Tel: (301) 496-2475
    On the web at: http://www.ncbi.nlm.nih.gov/Genbank/index.html
    <http://www.ncbi.nlm.nih.gov/Genbank/index.html>

Or

*EMBL Nucleotide Sequence Submissions*

    European Bioinformatics Institute,
    Hinxton Hall,
    Hinxton, Cambridge  CB10 1SD, UK
    Tel.: 44-1223-494401; Fax: 44-1223-494472
    e-mail:  support@ebi.ac.uk <mailto:support@ebi.ac.uk>
    On the web at:  http://www.ebi.ac.uk <http://www.ebi.ac.uk/>

Or

*DNA Data Bank of **Japan*

    Center for Information Biology
    National Institute of Genetics
    Mishima, Shizuoka, 411, Japan
    Tel.: 81-559-81-6853; Fax: 81-559-81-6849
    On the web at:  http://www.ddbj.nig.ac.jp <http://www.ddbj.nig.ac.jp/>


A footnote will be included in the paper indicating that such a deposit
has been made. Submission to any data bank is sufficient to ensure entry
in all. When nucleotide probes are used, the ends of the probes should
be explicitly identified by reference to published nucleotide number or
restriction maps, or, if unpublished, the information should be included
in the Experimental Procedures section.

Back to the top <#_top>


  Genomic and Proteomic Studies

Authors of papers that include genomic, proteomic, or other
high-throughput data are required to submit their data to the NCBI gene
expression and hybridization array data repository (GEO,
http://www.ncbi.nlm.nih.gov/geo/) and to provide the GEO accession
number. The data must be submitted and an accession number obtained
BEFORE the Associate Editor accepts the paper. Release of the
information in the database must be available at the time of acceptance
because they are published immediately as papers in press.Access to the
information in the database must be available at the time of publication.

GEO has a web-based submission route, suitable for a small number of
samples, or a batch submission tool (called SOFT). GEO is accessible
from http://www.ncbi.nlm.nih.gov/geo/. Submission FAQ is at:
http://www.ncbi.nlm.nih.gov/geo/info/general_faq.cgi.

Submitted data is encouraged to follow the MIAME checklist (for more
information see http://www.mged.org/Workgroups/MIAME/miame_checklist.html).

Back to the top <#_top>


  Structural Studies

For papers describing structures of biological macromolecules, the
atomic coordinates and the related experimental data (structure factor
amplitudes/intensities and/or NMR restraints) must be deposited at a
member site of the Worldwide Protein Data Bank (www.wwpdb.org
<http://www.wwpdb.org>): RCSB PDB (www.pdb.org <http://www.pdb.org>),
MSD-EBI (www.ebi.ac.uk/msd <http://www.ebi.ac.uk/msd>), PDBj
(www.pdbj.org <http://www.pdbj.org>), or BMRB (www.bmrb.wisc.edu
<http://www.bmrb.wisc.edu>). The PDB ID should be included in the
manuscript. Authors must agree to release the atomic coordinates and
experimental data when the associated article is published. Questions
relating to depositions should be sent to info@wwpdb.org
<mailto:info@wwpdb.org>.
Authors must supply all information BEFORE the paper is accepted by the
Associate Editor. After completion of the editorial process, the
manuscript will /not/ be accepted until confirmation has been received
from the author, if not initially supplied, that the required
information has been deposited and will be available BEFORE acceptance.
No data is to be withdrawn from PDB once a paper has been accepted and
published as a Papers in Press (PIP) article.

As of 12/06, PDB no longer accepts coordinates for model structures
determined by computational methods. The coordinates must be included as
a supplement to the online paper and formatted just as if it were a PDB
submission.

Click here for additional guidelines
<http://www.jbc.org/misc/Cryst_Guidelinesfin2.pdf>

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  Database Accession Hyperlinks For JBC On-line

The electronic version of the JOURNAL employs direct hyperlink access to
entries in databases such as GenBank. Authors are required to provide
accession numbers to databases for all newly described molecular
structures reported in their manuscripts.

In addition, authors are strongly encouraged to include accession
numbers for any database information that would aid a reader in
understanding the authors' paper regardless of who had deposited the
database information.

In order for the database hyperlinks to be generated, the citation must
appear as a Footnote and be written exactly as follows:

   1. GenBank = GenBank Accession Number XYYYYY
   2. Molecular Modeling Database = MMDB # XYYY
   3. NCBI Protein Database = NCB Accession # XXXXX
   4. Swiss Protein Database = Swiss-Prot # XXXX
   5. Enzyme Collection Number = xx.yy.zz.bb
   6. Research Collaboratory for Structural Bioinformatics Protein
      Databank = PDB # XXXX

The molecule or structure for an accession number can be identified
through the NCBI Entrez utility at http://www.ncbi.nlm.nih.gov/Entrez/.

The following shows how references to databases should be written in a
footnote.
"The nucleotide sequence for the artificial sperm whale myoglobin gene
has been deposited in the GenBank database under GenBankAccession Number
(Reference). The amino acid sequence of this protein can be accessed
through NCBI Protein Database under NCBI Accession # 2311060
(Reference). The atomic coordinates for the crystal structure of this
protein are available in the Molecular Modeling Database
(http://www.nnlm.nlm.nih.gov/mar/molbio/3D/index.htm) under MMDB #
5MBN(Reference)."

Authors may include their email address and home page URL. However,
authors cannot cite in the manuscript that additional data not presented
in the manuscript are available at the homepage. Home page URLs will not
be hyperlinked.

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