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  JOURNALS

Home </>  /  Medicine and Healthcare </browse/?subject=MEDI>  / 
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The Journal of Pathology


    The Journal of Pathology

*See Also:*

    * The Journal of Pathology 1892-1995 </journal/110526247/home>

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Copyright © 2007 Pathological Society of Great Britain and Ireland.
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        Instructions to Authors


*Aims and Scope*

The main interests of /The Journal of Pathology/ lie in the
pathophysiological and pathogenetic mechanisms of human disease and in
the application of such knowledge to diagnosis and prognosis. In
determining content, the primary considerations are excellence,
relevance and novelty.

The Journal welcomes investigative studies on human tissues,
experimental studies /in vitro/ and /in vivo/ , and investigations based
on animal models with a clear relevance to human disease, including
transgenic systems. Methodological improvements in investigative and
diagnostic pathology are also of interest. Correlative studies of
pathological data and clinical outcomes are considered but purely
descriptive papers on diagnostic pathology are not considered central to
the Journal's purpose. In general, studies that appropriately employ
multiple investigative techniques are preferred over those that rely on
a single methodology. Illustrations must be of the highest quality to be
acceptable for publication. As well as original research papers, the
Journal seeks to provide rapid publication in a variety of other
formats, including editorials, review articles and other features, both
contributed and solicited. Papers covering significant developments in
teaching methods and in the practice of pathology may be acceptable if
they are of international scope and relevance. Correspondence from
readers will be published if it is of general interest.

In summary, the Journal aims to serve as a bridge between basic
biomedical science and clinical medicine with particular emphasis on
morphologically based studies. As the journal of The Pathological
Society, it seeks to reflect the broad scientific interests of the
Society's membership, but its ethos, authorship, content and purpose are
those expected of a leading publication in the international scientific
literature.

*The Review Process*

Manuscripts are assigned sequentially to Associate Editors. An Associate
Editor solicits reviewers (typically, two external reviews are sought).
The reviewers? evaluations and Associate Editor?s comments are compiled
by the Editor-in-Chief for disposition and transmittal to the authors. A
decision is made usually within six weeks of the receipt of the manuscript.

The Editor-in-Chief will advise authors whether a manuscript is
accepted, should be revised or is rejected. Minor revisions are expected
to be returned within four weeks of decision; major revisions within
three months. Manuscripts not revised within these time periods are
subject to withdrawal from consideration for publication unless the
authors can provide extenuating circumstances.

A number of manuscripts will have to be rejected on the grounds of
priority and available space. A manuscript may be returned to the
authors without outside review if the Editor-in-Chief and Associate
Editor find it inappropriate for publication in the Journal. Similarly,
the Editors may expedite the review process for manuscripts felt to be
of high priority in order to reach a rapid decision. Such ?fast-track
decisions? will normally occur within one week of receipt of the manuscript.

Authors may provide the Editor-in-Chief with the names, addresses and
email addresses of up to three suitably qualified individuals of
international standing who would be competent to referee the work,
although the Editor-in-Chief will not be bound by any such nomination.
Likewise, authors may advise of any individual who for any reason, such
as potential conflict of interest, might be inappropriate to act as a
referee, again without binding the Editor-in-Chief.

The Editor-in-Chief ?s decision is final. If, however, authors dispute a
decision and can document good reasons why a manuscript should be
reconsidered, a rebuttal process exists. In the first place, authors
should write to the Editor-in-Chief.

*Declaration*

/Original publication/

Submission of a manuscript will be held to imply that it contains
original unpublished work and is not being submitted for publication
elsewhere at the same time. This should be confirmed to the editor in
the covering letter. The author must supply a full statement to the
Editor-in-Chief about all submissions and previous reports that might be
regarded as redundant or duplicate publication of the same or very
similar work.

/Conflict of interest/

Authors are responsible for disclosing all financial and personal
relationships between themselves and others that might bias their work.
To prevent ambiguity, authors must state explicitly whether potential
conflicts do or do not exist. Investigators should disclose potential
conflicts to study participants and should state in the manuscript
whether they have done so. Authors should describe the role of the study
sponsor(s), if any, in study design, in the collection, analysis and
interpretation of data, in the writing of the report and in the decision
to submit the report for publication. If the study sponsor(s) had no
such involvement, the authors should so state. A conflict of interest
statement must be included in the manuscript (on the title page) that
details any conflicts that exist for each author, or declares the
absence of conflict for each author. For further information and
guidance on disclosing conflicts of interest, please visit our conflicts
of interest page <PATH_COIguidancepage.doc>

/Ethics/

A statement describing explicitly the ethical background to the studies
being reported should be included in all manuscripts in the Materials
and Methods section. Ethics committee or institutional review board
approval should be stated. When reporting experiments on human subjects,
indicate whether the procedures followed were in accordance with the
ethical standards of the responsible committee on human experimentation
(institutional or regional) and with the Helsinki Declaration of 1975,
as revised in 1983. Do not use patients? names, initials or hospital
numbers, especially in illustrative material. When reporting experiments
on animals, indicate whether the institution?s or a national research
council?s guide for, or any national law on, the care and use of
laboratory animals was followed.

Patients have a right to privacy that should not be infringed without
informed consent. Identifying information should not be published in
written descriptions, photographs and pedigrees unless the information
is essential for scientific purposes and the patient (or parent or
guardian) gives written informed consent for publication. Informed
consent for this purpose requires that the patient be shown the
manuscript to be published. Identifying details should be omitted if
they are not essential but patient data should never be altered or
falsified in an attempt to attain anonymity. Complete anonymity is diff
icult to achieve and informed consent should be obtained if there is any
doubt. For example, masking the eye region in photographs of patients is
inadequate protection of anonymity.

/Authorship/

All persons designated as authors should qualify for authorship and all
those who qualify should be listed. Each author should have participated
sufficiently in the work to take public responsibility for appropriate
portions of the content. One or more authors should take responsibility
for the integrity of the work as a whole, from inception to published
article.

Authorship credit should be based only on 1) substantial contributions
to conception and design, or acquisition of data, or analysis and
interpretation of data; 2) drafting the article or revising it
critically for important intellectual content; 3) final approval of the
version to be published. Conditions 1, 2 and 3 must all be met.
Acquisition of funding, the collection of data or general supervision of
the research group, by themselves, do not justify authorship. All others
who contributed to the work who are not authors should be named in the
Acknowledgements section.

/COPE/

As a member of the Committee on Publication Ethics (COPE), adherence to
these submission criteria is considered essential for publication in The
Journal of Pathology; mandatory fields are included in the online
submis- sion process to ensure this. If, at a later stage in the
submission process or even after publication, a manuscript or authors
are found to have disregarded these criteria, it is the duty of the
Editor-in-Chief to report this to COPE. COPE may recommend that action
may be taken, including but not exclusive to, informing the authors?
professional regulatory body and/or institution of such a dereliction.

The website for COPE may be accessed at:
http://www.publicationethics.org.uk <http://www.publicationethics.org.uk/>

*Preparation of Manuscript*

The text of observational and experimental articles is divided into
sections with the headings: Abstract, Introduction, Methods, Results and
Discussion. Long articles may need subheadings within some sections
(especially the Results and Discussion sections) to clarify their
content. Other types of articles, such as reviews and commentaries,
still need a title and abstract and should adhere as closely as possible
to the guidelines.

Research reports must not omit any important information, raw data
necessary for review must be made available (as Supplementary Material)
and submission to the journal is taken to indicate agreement to share
novel reagents that are not commercially available with other
researchers. Authors are encouraged to consult reporting guidelines
relevant to their specific research design, in particular:

    * For reports of randomised controlled trials, follow the CONSORT
      statement http://www.consort-statement.org .
    * For reports of tumour studies, adhere to the REMARK guidelines
      http://www.cancerdiagnosis.nci.nih.gov/assessment/progress/remark.html
      .
    * For microarray analyses, follow the MIAME guidelines
      http://www.mged.org/Workgroups/MIAME/miame.html and submit your
      data to the GEO or Array Express database prior to submission
      (release embargos until acceptance are permitted), quoting the
      accession number/s in your manuscript.

Format a Word document to A4 paper with margins of at least 20 mm all
round. Ensure page numbering is included in either the header or footer
and aligned right. Use a standard widely used font such as Times or
Arial with Symbol for special characters. Each table should be on a
separate page in landscape orientation if necessary. Figures and
illustrations must not be included or embedded into the document but
uploaded as separate files.

*Title Page*

The title page should carry 1) the full title and a suggested short
title of the article; 2) the name by which each author is known and
institutional affiliation; 3) the name of the department(s) and
institution(s) to which the work should be attributed; 4) disclaimers,
if any; 5) source(s) of support in the form of grants, equipment, drugs
or all of these; 6) an accurate word count of the text from the start of
the introduction to the end of the discussion; 7) a conflict of interest
statement.

*Abstract*

The second page should carry an abstract, in prose form (not
structured), of up to 300 words. The abstract should state the purposes
of the study or investigation, the basic procedures, the main findings
and the principal conclusions. It should emphasise new and important
aspects of the study or observations. It should be understandable
without reference to the rest of the paper and should contain no
citation to other published work.

*Key Words*

Below the abstract authors should provide and identify as such 3 to 10
key words or short phrases to assist indexing the article and that may
be published with the abstract. At least 3 of the keywords should refer
to the anatomical site, disease and techniques used in the study.

*Main Text*

There are approximately 900 words on a full printed page of journal
text. Full articles should not exceed 3000 words from the beginning of
the Introduction to the end of the Discussion, which is approximately
six journal pages, when tables, figures and references are also
included. Short articles should not exceed four journal pages, including
tables, figures and references. Review articles and special features may
exceed these limits by arrangement with the Editor-in-Chief. Succinct
articles are likely to make a greater impact on readers than long ones
and are more likely to be accepted for publication without delay.

*Introduction*

State the purpose of the article and summarise the rationale for the
study or observation. Give only strictly pertinent references and do not
include data or conclusions from the work being reported.

*Methods*

Clearly describe your selection of the observational or experimental
subjects (patients or laboratory animals, including controls). Identify
the age, sex and other important characteristics of the subjects where
appropriate. As the relevance of such variables as age, sex and
ethnicity to the object of research is not always clear, authors should
explicitly justify them when they are included in a study report. The
guiding principle should be clarity about how and why a study was
performed in a particular way. Authors should avoid terms such as ?race?
which lacks precise biological meaning and use alternative descriptors
such as ?ethnicity? or ?ethnic group? instead. Authors should specify
carefully what the descriptors mean and tell exactly how the data were
collected.

Identify the methods, apparatus (give the manufacturer?s name and
address in parentheses) and procedures in sufficient detail to allow
other workers to reproduce the results. Give references to established
methods, including statistical methods (see below); provide references
and brief descriptions for methods that have been published but are not
well known; describe new or substantially modified methods, give reasons
for using them and evaluate their limitations. Identify precisely all
drugs and chemicals used, including generic name(s), dose(s) and
route(s) of administration.

Reports of randomised clinical trials should present information on all
major study elements, including the protocol (study population,
interventions or exposures, outcomes and the rationale for statistical
analysis), assignment of interventions ( methods of randomisation,
concealment of allocation to treatment groups) and the method of masking
(blinding).

Authors submitting review manuscripts should include a section
describing the methods used for locating, selecting, extracting and
synthesising data. These methods should also be summarised in the abstract.

*Statistics*

Describe statistical methods with enough detail to enable a
knowledgeable reader with access to the original data to verify the
reported results. When possible, quantify findings and present them with
appropriate indicators of measurement error or uncertainty (such as
confidence intervals) References for the design of the study and
statistical methods should be to standard works when possible (with
pages stated) rather than to papers in which the designs or methods were
originally reported.

Restrict tables and figures to those needed to explain the argument of
the paper and to assess its support. Use graphs as an alternative to
tables with many entries; do not duplicate data in graphs and tables.
Avoid non-technical uses of technical terms in statistics, such as
?random? (which implies a randomising device), ?normal?, ?significant?,
?correlations? and ?sample?.

*Results*

Present your results in logical sequence in the text, tables and
illustrations. Do not repeat in the text all the data in the tables or
illustrations; emphasise or summarise only important observations.

*Discussion*

Emphasise the new and important aspects of the study and the conclusions
that follow from them. Do not repeat in detail data or other material
given in the Introduction or the Results section. Include in the
Discussion section the implications of the findings and their
limitations, including implications for future research. Relate the
observa tions to other relevant studies.

Link the conclusions with the goals of the study but avoid unqualified
statements and conclusions not completely supported by the data. In
particular, authors should avoid making statements on economic benefits
and costs unless their manuscript includes economic data and analyses.
Avoid claiming priority and alluding to work that has not been
completed. State new hypotheses when warranted but clearly label them as
such. Recommendations, when appropriate, may be included. References to
unpublished data should not be included.

*Acknowledgements*

List all contributors who do not meet the criteria for authorship, such
as a person who provided purely technical help, writing assistance or a
department chair who provided only general support. Financial and
material support should also be acknowledged.

Groups of people who have contributed materially to the paper but whose
contributions do not justify authorship may be listed under a heading
such as ?clinical investigators? or ?participating investigators? and
their function or contribution should be described.

*References*

References should be numbered consecutively in the order in which they
are first mentioned in the text. Identify references in text, tables and
legends by Arabic numerals in square parentheses. References cited only
in tables or figure legends should be numbered in accordance with the
sequence established by the first identification in the text of the
particular table or figure. All references should be complete and accurate.

Avoid using abstracts as references. References to papers accepted but
not yet published should be designated as ?in press?; authors should
obtain written permission to cite such papers as well as verification
that they have been accepted for publication. Copies of any papers cited
as ?in press? must be included in the submission. Avoid using
unpublished observations and information from manuscripts submitted but
not accepted.

Avoid citing a ?personal communication? unless it provides essential
information not available from a public source, in which case the name
of the person and date of communication should be cited in parentheses
in the text. Authors must supply written permission and confirmation of
accuracy from the source of a personal communication.

The Journal?s reference style is modified Vancouver used by the NLM in
Index Medicus. For articles with more than 6 authors, only the first 6
authors should be listed, followed by /et al/ . The titles of journals
should be abbreviated according to the style used in Index Medicus.
Title abbreviations can be checked using the PubMed Journals database:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=journals&term= .
Articles published online but not yet assigned to an issue may be cited
using the DOI (see example 4). Online citations should include the date
of access.

   1. Going JJ, Moffat DF. Escaping from Flatland: clinical and
      biological aspects of human mammary duct anatomy in three
      dimensions. /J Pathol/ 2004; *203* :538?544.
   2. Watson F, Herrington CS. Blotting techniques: Methodology and
      Applications. In /Molecular Biology in Histopathology/ , (2nd
      edn), Crocker J, Murray PG (eds). John Wiley & Sons Ltd:
      Chichester, 2003; 1?15.
   3. Stevens A, Lowe J. /Pathology/ (2nd edn). Mosby: London, 2000;224?226.
   4. L Strizzi, C Bianco, M Hirota, K Watanabe, M Mancino, S Hamada /et
      al./ Development of leiomyosarcoma of the uterus in MMTV-CR-1
      transgenic mice. /J Pathol/ 2006; DOI:10.1002/path.2083
   5. Wright NA. /The Standing of UK Histopathology Research 1997-2002/
      . www.pathsoc.org.uk/ [accessed 7 October 2004].

*Tables*

Type each table on a separate page at the end of the main document. Do
not submit tables as photographs. Number tables consecutively in the
order of their first citation in the text and supply a brief title for
each. Give each column a short or abbreviated heading. Place explanatory
matter in footnotes, not in the heading. Explain in footnotes all
non-standard abbreviations that are used in each table. Identify
statistical measures of variations, such as standard deviation and
standard error of the mean. Do not use internal horizontal and vertical
rules. Be sure that each table is cited in the text. If you use data
from another published source, obtain permission and acknowledge fully.

*Illustrations (Figures)*

Figures should be numbered consecutively according to the order in which
they have been first cited in the text. If a figure has been published,
acknowledge the original source. If the manuscript is accepted for
publication, written permission from the copyright holder to reproduce
the material will have to be supplied. Permission is required
irrespective of authorship or publisher except for documents in the
public domain. Permission request forms can be downloaded from the
Journal's website on Wiley InterScience under 'For Authors':
http://www.interscience.wiley.com/thejournalofpathology If photographs
of people are used, either the subjects must not be identifiable or
their pictures must be accompanied by written permission to use the
photograph (see Ethics).

Figures should be professionally drawn, photographed and digitised;
freehand or typewritten lettering is unacceptable. Letters, numbers and
symbols should be clear and even throughout and of sufficient size that
when reduced for publication each item will still be legible. Titles and
detailed explanations belong in the legends for illustrations not on the
illustrations themselves.

*Figure Format*

Figures should be scaled to fit either one or two column widths (83 mm
and 170.5 mm respectively) with a maximum height of 251.5 mm. Figures
should be supplied (uploaded) as tiff files in RGB or greyscale mode
with no profile embedded and no layers. All illustrations must be
supplied at the correct resolution:

    * Black and white and colour photos ? 300 dpi
    * Graphs, drawings, etc ? 800 dpi preferred; 600 dpi minimum
    * Combinations of photos and drawings (black and white and colour) ?
      500 dpi

Authors should be careful to check that their colour images (especially
fluorescence) will reproduce faithfully in CMYK print before submission
(see additional resources in the Editorial: ?The Journal of Pathology
moves forward? by C. Simon Herrington, Jeremy J Theobald, Simon D Newton
and Martin A Smart ( /The Journal of Pathology/ , Volume 204, Issue 5,
Pages 507-509 <http://dx.doi.org/10.1002/path.1678> ) with supplementary
material at
http://www.mrw.interscience.wiley.com/suppmat/0022-3417/suppmat/path.1678.html.)
<http://www.mrw.interscience.wiley.com/suppmat/0022-3417/suppmat/path.1678.html>

We recommend that authors check the quality of their figures prior to
submission using Sheridan's Digital Expert tool
http://dx.sheridan.com/index.html. <http://dx.sheridan.com/index.html>

*Legends for Illustrations*

Type legends for illustrations starting on a separate page with Arabic
numerals corresponding to the illustrations. When symbols, arrows,
numbers or letters are used to identify parts of the illustrations,
identify and explain each one clearly in the legend. Do not indicate the
magnification for light micrographs. Internal scale markers are
recommended for electron micrographs. Indicate the type of stain used
only if it is other than haematoxylin and eosin.

*Page charges*

There is no page charge to authors. The cost of printing colour
illustrations in the journal is currently £400 per colour page and will
be charged to the author. In exceptional circumstances, if colour
reproduction is considered essential by the referees and if the authors
and their institutions or funding agencies are unable to meet the full
cost, publication of colour may be made available at a reduced rate. The
funds available for this purpose are limited and will be employed at the
discretion of the Editor-in-Chief. Authors wishing to seek this subsidy
should explain the circusmstance to the Editor-in-Chief on submission of
the manuscript.

If authors wish their illustrations to be printed in black and white,
figures must be supplied and reviewed in black and white with
appropriate contrast and brightness adjustments made for the best
possible reproduction.

*Units of Measurement*

Measurements of length, height, weight and volume should be reported in
metric units ( metre, kilogram or litre) or their decimal multiples.
Temperatures should be given in degrees Celsius. Blood pressures should
be given in millimetres of mercury. All haematological and clinical
chemistry measurements should be reported in the metric system in terms
of the International System of Units (SI).

*Abbreviations and Symbols*

Use only standard abbreviations. Avoid abbreviations in the title and
abstract. The full term for which an abbreviation stands should precede
its first use in the text unless it is a standard unit of measurement.

*Copyright*

To enable the publisher to disseminate authors? work to the fullest
extent, all authors must sign a Copyright Transfer Agreement,
transferring copyright in the article from the authors to The
Pathological Society of Great Britain and Ireland. An agreement with
original signatures will be requested if a paper is accepted for
publication. A copy of the agreement to be used (which may be
photocopied) can be found in the first issue of each volume of /The
Journal of Pathology/ . Copies may also be obtained from the editorial
office, from the journal website or the on-line submission website.

*Checklist of Manuscript Requirements* .

    * Follow the correct sequence: Title Page, Abstract and Key words,
      Introduction, Methods, Results and Discussion, Acknowledgements,
      References, Tables (each on a separate page), Legends.
    * Begin each section or component on a new page.
    * Illustrations should be no larger than 83 × 251.5 mm (one column
      width) or 170.5 × 251.5 mm (two column width) and reach the
      resolution standards set by journal policy (see above).
    * Supply (upload) only one Word file and only high-resolution TIFF
      files as illustrations.
    * Keep copies of everything submitted.

*Sending the Manuscript*

Submission to /The Journal of Pathology/ is only via an online system at
http://mc.manuscriptcentral.com/jpath . Prepare your manuscript and
illustrations in the appropriate format, according to these
instructions. Please also be sure that your paper conforms to the
scientific and style instructions of the Journal.

If you are unsure of your password, click ?Forgot Your Password?? If you
have an account, you will be asked to enter your contact email and a
temporary password will be sent to you so that you can access your
manuscript. If you do not have an account, you can create one for
yourself in the system at the submission site by clicking on the ?Create
Account? button. Subsequently, to monitor the progress of your
manuscript throughout the review process, just login periodically and
check your Author Centre.

When you are ready to submit your manuscript, let the system guide you
through the submission process. Online help is available to you at all
times during the process by clicking ?Get Help Now? in the upper
right-hand corner of the screen. You are also able to exit/re-enter the
process at any stage before finally submitting your work.

/LATEX users./ For your original submission you should upload a single
.pdf that you have generated from your source files. You must use the
File Designation "Main Document" from the dropdown box. When submitting
a revision you must still upload a single .pdf that you have generated
from your now revised source files. You must use the File Designation
"Main Document" from the dropdown box. In addition you must upload your
TeX source files. For all your source files you must use the File
Designation "Supplemental Material not for review". Previous versions of
uploaded documents must be deleted. If your manuscript is accepted for
publication we will use the files you upload to typeset your article
within a totally digital workflow.

All hard copy and emailed manuscripts sent to the Editor-in-Chief, the
Editorial Office or The Pathological Society will be returned to authors
with instructions to submit online.

*English Checking Service for Authors in Asia (from non-English speaking
countries)*

A list of recommended English editing services is available for authors
who want to have their paper checked and improved before submission.
This list and further information on the service is available at
http://www.wiley.co.jp/editservlist.html Please note that this is an
optional service paid for by the author. For any queries please contact
the Wiley Tokyo editorial office by fax on +81 3556 9763 or email
editorial@wiley.co.jp.

*Further Information*

The e-mail address for the Editorial Office is
managing_editor@jpathol.org This email address is for correspondence and
not for the submission of manuscripts.

Failure to abide by the guidelines for submission to /The Journal of
Pathology/ may result in undue delay in the submission, review or
publication of your manuscript.

Proofs will be sent to the author for checking. This stage is to be used
only to correct errors that may have been introduced during the
production process. Prompt return of the corrected proofs, preferably
within two days of receipt, will minimise the risk of the paper being
held over to a later issue.

Twenty-five complimentary offprints of papers will be provided to the
author who checked the proofs, unless otherwise indicated. Further
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